Search on: 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (B-SPECIFIC) 
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Descriptor English:   3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) 
Descriptor Spanish:   3-alfa-Hidroxiesteroide Deshidrogenasa (B-Específica) 
Descriptor Portuguese:   3-alfa-Hidroxiesteroide Desidrogenase (B-Específica) 
Tree Number:   D08.811.682.047.436.350.100
D08.811.682.047.820.186
Definition English:   A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA,17 BETA-DIOL. It also has activity towards other 3-alpha-hydroxysteroids and on 9-, 11- and 15- hydroxyprostaglandins. The enzyme is B-specific in reference to the orientation of reduced NAD or NADPH. 
History Note English:   2004; use 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (B-SPECIFIC) (NM) 1979-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   38201 
Unique Identifier:   D045002 

Occurrence in VHL:
 

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